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Faculty and Student
Teams Program
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Project Descriptions
Lawrence
Berkeley National Laboratory
Department of Nuclear Medicine and Functional Imaging
Requesting applications from science or engineering faculty members at
institutions serving students underrepresented in science, engineering,
mathematics and technology. To work in the development of new radiopharmaceuticals
to image the serotonergic system.
Project Description
The overall goal of this project is to design, synthesize and test new radiopharmaceuticals
that can be used in non-invasive imaging of the brain's serotonergic system.
This work will involve computer-based molecular modeling of new ligands,
the synthesis and radiolabeling of these ligands, and their evaluation through
a series of in vivo and in vitro binding and metabolic studies. Knowledge
gained from these studies will be used to design and produce successive
generations of radioligands, until one is developed that can be utilized
in clinical studies. This project requires a multidisciplinary approach,
involving collaborations between organic and radiochemists, biochemists,
and neurophysiologists that are all members of the departmental staff.
Applicants Responsibilities and Relationship to Project
Applicants and their students will receive support under the Department
of Energy Faculty and Student Team (FaST) program to work collaboratively
with a research group at Berkeley Lab for 10 weeks during the summer of
2008. Faculty and students
team members will be assigned to the same research group and typically
faculty participants will provide mentorship and/or advising support to
the undergraduate student team members while at the Lab.
Applicants are encouraged to contact Berkeley Lab investigators
offering FaST opportunities during the application process.
Following the summer appointment, it is anticipated that the
faculty participants will establish a ongoing collaborative relationship
with Berkeley Lab investigators and assist in recruiting undergraduate
students from their campus for DOE internship programs.
Qualifications of Ideal Candidate
| Faculty: |
Ph.D. in chemistry with interest in the synthesis of new pharmaceutical
compounds. Some experience in computer-based design of new pharmaceuticals
desired. Established record of publication in field is preferred.
Currently teaches and collaborates with students in his/her field.
Willing to work at LBNL for an extended period (2-3 summer months,
or longer). |
| Student: |
Working towards a BS or BA in chemistry, biochemistry or pharmaceutical
science. Works well in collaboration with other students, and researchers.
Some previous experience working independently in a laboratory setting.
Willing to work at LBNL for an extended period. |
Support
and Financial Commitments
See Financial
Information.
For More Information Contact:
Laurel
Egenberger
Manager
College
& University Programs
Lawrence
Berkeley
National Laboratory
E-mail: LLEgenberger@lbl.gov
Phone: 510-486-5190 |
Scott Taylor
Department of Nuclear Medicine and
Functional Imaging
E-mail: SETaylor@lbl.gov
Phone: 510-486-4103 |
http://csee.lbl.gov/
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