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Faculty and Student Teams Program

questioning Project Descriptions

Pacific Northwest National Laboratory
Analytical Chemistry Group

Requesting applications from science or engineering faculty members at institutions serving students underrepresented in science, engineering, mathematics and technology.

Project Description

The project will involve the development of analytical techniques for the analysis of trace quantities of organic compounds in non-invasive and invasive biological matrices that may be indicators of environmental exposure. For example, we are evaluating saliva as a non-invasive biomonitoring matrix for the determination of exposure to organophosphate insecticides. We have been shown that there is a correlation between the concentrations found in blood and saliva of rats exposed to chlorpyrifos, an organophosphate insecticide. Additional work is required to determine if saliva can be used as a biomonitoring matrix at environmentally important levels for other organophosphate insecticides and various industrial chemicals, as well as an indicator of disease or other stress inducing events

Applicants Responsibilities and Relationship to Project

Applicants will receive support under the Department of Energy's Faculty Student Team (FaST) Research Program to work collaboratively with the project research team at the Pacific Northwest National Laboratory for 10 weeks, starting in May/June of 2006. The faculty member will identify two undergraduate students from their campus to participate as a team in this undergraduate research participation program. The faculty member will provide leadership and/or advising support to students during the summer research activities and will participate in all endeavors as part of the research team. It intended that the faculty member will become an integral part of the research team and will support the project through the academic year on her or his campus. The FaST team will submit a formal research paper illustrating their accomplishments to be considered for publication in the U.S. Department of Energy's Journal of Undergraduate Research.

Qualifications of Ideal Candidate

Faculty: M.S. Degree in chemistry. Experience preparing limited quantities of complex matrices, chemical separations, and mass spectrometry. Interest in analytical chemistry.
Student: Majoring in chemistry, biology, or pharmacy and possessing adequate interest, maturity, and discipline to be active members of the research team.

Support and Financial Commitments

See Financial Information.

For More Information contact:

Royace Aiken, Program Manager
Pacific Northwest National Laboratory
E-mail: royace.aikin@pnl.gov
(509) 375-6929
http://science-ed.pnl.gov/index.stm

Jim Campbell and Eric Hoppe
Chemical Analysis Group
National Security Directorate
Pacific Northwest National Laboratory
Box 999, P8-08
Richland, WA 99352
(509) 376-0899 and (509) 376-2329
james.campbell@pnl.gov
eric.hoppe@pnl.gov